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GlossaryC3H mouse

specific lab mouse strain used in cancer and hair loss research

A C3H mouse is a specific strain of laboratory mouse that is commonly used in scientific research. This strain is known for its susceptibility to developing certain types of cancers and for its use in studies related to immunology, genetics, and aging. The C3H mouse is also notable for its role in hair research, as it can develop alopecia areata, an autoimmune condition that causes hair loss, making it a valuable model for studying this disease.

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research Characterization of Dermal Type I Collagen of C3H Mouse at Different Stages of the Hair Cycle

15 citations , October 1999 in “British Journal of Dermatology”

Collagen remodeling is more active during hair growth stages.

research Evaluation of Hair Regrowth by Cyclosporine and Minoxidil Using C3H Mouse Model

July 1995 in “Journal of Dermatological Science”

Cyclosporine starts hair growth faster, while minoxidil makes it last longer.

research Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans

114 citations , August 2002 in “Journal of Investigative Dermatology”

Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.

research Study on Histamine Related Enzyme Activities During Murine Hair Cycle

4 citations , January 1997 in “EXPERIMENTAL ANIMALS”

Histamine and its enzyme may help start hair regrowth.

research Modeling of Chronic Radiation-Induced Cystitis in Mice

30 citations , August 2016 in “Advances in radiation oncology”

Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.

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community Natural Remedies: Polyphenols and Hair Loss

20 upvotes 6 years ago

Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

community TDM-105795 phase 2 results are in!

in Research/Science 29 upvotes 2 years ago

TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.