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DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

PCOS is common, affects fertility, and requires personalized treatment to manage symptoms and health risks.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Celiac disease requires more than just a gluten-free diet for effective management.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

The document concludes that breast pain should be managed with personalized treatment, starting with non-drug methods and progressing to medication if necessary, while considering side effects and patient needs.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Looking older on the outside might be linked to aging faster on the inside and can be affected by lifestyle choices and health risks.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Some nutrients and antioxidants may improve skin and hair health, but more research is needed to confirm these benefits.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

PRP may help with aging and osteoarthritis, improving tissue repair and reducing surgery risk.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

A girl with lupus and trisomy X has a higher risk of bone problems like avascular necrosis and osteoporosis.

A woman with anorexia and Cushing's syndrome improved after tumor removal, highlighting the need to consider hormonal issues in psychiatric conditions.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.

Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.

Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.