Label Retaining Cells with Myoepithelial Characteristics from the Proximal Acinar Region Define Stem Cells in the Sweat Gland

    September 2013 in “ PLoS ONE ”
    Yvonne Leung, Eve Kandyba, Yibu Chen … Krzysztof Kobielak
    Studysummary This study found that sweat gland stem cells primarily maintain sweat gland homeostasis but can trans-differentiate to aid in epidermal healing and regenerate diverse skin structures under certain conditions.
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    Research cited in this study 12

    1. Competitive Balance of Intrabulge BMP/Wnt Signaling Reveals a Robust Gene Network Ruling Stem Cell Homeostasis and Cyclic Activation Proceedings of the National Academy of Sciences · 2013
    2. Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair Cell · 2012
    3. Distinct Stem Cells Contribute to Mammary Gland Development and Maintenance Nature · 2011
    4. TCF/Lef1 Activity Controls Establishment of Diverse Stem and Progenitor Cell Compartments in Mouse Epidermis The EMBO Journal · 2011
    5. Human Eccrine Sweat Gland Cells Can Reconstitute a Stratified Epidermis Journal of Investigative Dermatology · 2010
    6. The Localization of Label-Retaining Cells in Eccrine Glands Journal of Investigative Dermatology · 2009
    7. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    8. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005
    9. Morpho-Regulation of Ectodermal Organs ˜The œAmerican journal of pathology · 2004
    10. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    11. Conditional Gene Expression in the Epidermis of Transgenic Mice Using the Tetracycline-Regulated Transactivators tTA and rTA Linked to the Keratin 5 Promoter Journal of Investigative Dermatology · 2000
    12. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000

    Related research 4

    1. Isolation and Characterization of Sweat Gland Myoepithelial Cells from Human Skin Cell Structure and Function · 2014
    2. Keratins of the Human Hair Follicle International review of cytology · 2005
    3. Hair Follicle Differentiation And Regulation The International Journal of Developmental Biology · 2004
    4. Hair Keratin Pattern in Human Hair Follicles Grown In Vitro Experimental dermatology · 2003