research Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism
Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.
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research Finasteride in the Treatment of Hirsutism: New Therapeutic Perspectives
Finasteride effectively treats hirsutism in women, but more research needed for long-term results.
research Nutrition Strategy and Lifestyle in Polycystic Ovary Syndrome: Narrative Review
Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.
research Nanoparticles in Wound Healing: From Hope to Routine
Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
research Wnt Signaling: The Good and the Bad
Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
research Polycystic Ovary Syndrome and Other Androgen Excess-Related Conditions: Can Changes in Dietary Intake Make a Difference?
Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.
research The Human Skin Microbiome in Selected Cutaneous Diseases
Changes in skin microbes play a role in some skin diseases and could lead to new treatments.
research Jojoba Oil: An Updated Comprehensive Review on Chemistry, Pharmaceutical Uses, and Toxicity
Jojoba oil is highly valued for its diverse medicinal and industrial uses.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research Androgens Modify Wnt Agonists/Antagonists Expression Balance in Dermal Papilla Cells Preventing Hair Follicle Stem Cell Differentiation in Androgenetic Alopecia
Androgens prevent hair growth by changing Wnt signals in cells.
research The Pharmacology of Regenerative Medicine
Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
research Putative Role for Insulin Resistance in Depression Risk in Polycystic Ovary Syndrome
Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
research Controllable Production of Transplantable Adult Human High-Passage Dermal Papilla Spheroids Using 3D Matrigel Culture
Researchers created hair-inducing human cell clusters using a 3D culture method.
research The Activin Binding Proteins Follistatin and Follistatin-Related Protein Are Differentially Regulated In Vitro and During Cutaneous Wound Repair
FLRG and follistatin have different roles in wound healing.
research Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal, and Prostate Cancer
Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
research Effects of Melatonin Administration on Mental Health Parameters, Metabolic and Genetic Profiles in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
Melatonin improved mental health and metabolism in women with PCOS.
research Endocrine Care of Transpeople Part I: A Review of Cross-Sex Hormonal Treatments, Outcomes, and Adverse Effects in Transmen
Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
research Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase Predominates in Human Sebaceous Glands
The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
research Androgen Receptor Gene CAG Repeat Polymorphism in Women with Polycystic Ovary Syndrome
Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.
research Curtailing Polycystic Ovary Syndrome: A Review of International Evidence-Based Guidelines and Implications
Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.
research Functional Skin Grafts: Where Biomaterials Meet Stem Cells
Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
research Environmental Stress But Not Subjective Distress in Children or Adolescents With Alopecia Areata
Kids with alopecia areata may experience more stress but not necessarily feel more anxious or depressed than others.
research Analysis of Protein Interactions by Surface Plasmon Resonance
Surface Plasmon Resonance is a useful tool for studying protein interactions and has potential for future technological advancements.
research Transient Mitochondrial DNA Double Strand Breaks in Mice Cause Accelerated Aging Phenotypes in a ROS-Dependent but p53/p21-Independent Manner
Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
research Polycystic Ovary Syndrome and Its Differential Diagnosis
The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.
research Dermocosmetic Aspects of Hair and Scalp
New hair products are being developed to keep hair and scalp healthy for everyone.
research Quercetin and Polycystic Ovary Syndrome: Current Evidence and Future Directions - A Systematic Review
Quercetin may help with PCOS symptoms, but more research is needed.
research Regulation of Melanocyte Stem Cells in the Pigmentation of Skin and Its Appendages: Biological Patterning and Therapeutic Potentials
Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
research NUDT15, FTO, and RUNX1 Genetic Variants and Thiopurine Intolerance Among Japanese Patients With Inflammatory Bowel Diseases
Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.