TLDR Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
The document summarizes a cross-sectional study of 301 women with polycystic ovary syndrome (PCOS) that examined the link between insulin resistance and depression risk, independent of BMI. The study found that 44% of the women were at risk for depression, with those at risk having higher BMI and elevated HOMA-IR levels. After adjusting for various factors, each unit increase in HOMA-IR was associated with a 7% increase in the odds of depression risk. The study concluded that insulin resistance is significantly associated with depression risk in women with PCOS and highlighted the importance of mental health assessment in the comprehensive care of PCOS patients. The study suggests a bidirectional relationship between insulin resistance and depression and calls for further research to clarify this association and develop effective intervention strategies.
48 citations,
February 2014 in “Fertility and Sterility” Women with PCOS often have hair loss, which is linked to acne or excess body hair but not to worse hormone or metabolic issues.
1540 citations,
October 2008 in “Fertility and Sterility” The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
4809 citations,
January 2004 in “Fertility and Sterility” The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.
11 citations,
November 2017 in “Electronic physician” Depression severity is not linked to PCOS markers like BMI, insulin resistance, or testosterone levels.
5 citations,
September 2021 in “Cureus” Depression in women with Polycystic Ovarian Syndrome (PCOS) is linked to insulin resistance and hyperandrogenism, and managing these can help reduce depression. Lifestyle changes and Cognitive Behavioral Therapy can be effective treatments.
4 citations,
July 2019 in “Children (Basel)” The review concludes that more research is needed to better improve the health outcomes for people with Polycystic Ovarian Syndrome.
35 citations,
July 2015 in “Journal of Affective Disorders” Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.
2 citations,
August 2021 in “Journal of Turkish sleep medicine” People with polycystic ovary syndrome are more likely to have poor sleep, restless legs syndrome, anxiety, and depression.