Evaluation of Affective Temperament and Anxiety–Depression Levels of Patients with Polycystic Ovary Syndrome

The study from 2015 examined the affective temperaments and anxiety-depression levels in 71 women with polycystic ovary syndrome (PCOS) and compared them to 50 healthy controls. The results showed that women with PCOS had significantly higher scores for most temperament subtypes, as well as higher anxiety, depression, and total scores on the Hospital Anxiety and Depression Scale (HADS). There was a significant positive correlation between BMI and irritable temperament, and between insulin levels and HADS depression scores in the PCOS group. Hirsutism score and menstrual irregularity were also correlated with higher HADS scores. Logistic regression analysis indicated that anxiety was associated with hirsutism score, but depression was not significantly affected by PCOS, hirsutism score, or menstrual irregularity. The study suggests that affective temperament could be an indicator of the risk for depressive and anxiety disorders in women with PCOS. However, the study's limitations include its cross-sectional design, reliance on self-rating scales, and a small sample size, which may affect the generalizability of the results.