Analysis of Protein Interactions by Surface Plasmon Resonance
January 2018
in “
Advances in protein chemistry and structural biology
”
TLDR Surface Plasmon Resonance is a useful tool for studying protein interactions and has potential for future technological advancements.
The document from 2018 provides a comprehensive overview of Surface Plasmon Resonance (SPR), a technique for analyzing protein interactions without labeling. It discusses the methodology, applications in basic science, diagnostics, and drug development, and future directions like SPR imaging and nanoparticle use. Studies are cited, including the immobilization of antibodies on SPR chips, development of antifouling materials, and novel DNA-sensing platforms. SPR's utility in studying various biological interactions, such as those related to immune response, neurochemistry, and diseases like Alzheimer's, is highlighted. The document also anticipates future advancements in SPR technology, including its potential to replace conventional methods in clinical analysis, the development of portable instruments, and the integration of nanoparticles to enhance detection capabilities.
