4 citations
,
January 2022 in “Drug design, development and therapy” This study demonstrated that intramuscular corticosteroids were effective for severe alopecia areata, with significant hair regrowth in 80.2% of patients, though a high relapse rate was noted post-treatment. Nail involvement and disease duration over six months negatively impacted outcomes.
3 citations
,
January 2024 in “Allergy Asthma and Immunology Research” This study explored the associations between the skin microbiome and metabolome in groups LS, NL, and HC, suggesting potential new pathways for understanding scalp involvement in AD patients, which could improve management strategies.
3 citations
,
April 2021 in “Journal of Clinical Medicine” This pilot study found that bacterial cultures in axillary lymph nodes, skin lesions, and fistulae matched in one hidradenitis suppurativa patient, but the small sample size limits definitive conclusions.
2 citations
,
May 2018 in “Journal of The American Academy of Dermatology” This study examined 15 female patients with hypothyroidism to investigate the characterization of their alopecia and ruled out other causes, using medical histories, and clinical, trichoscopic, and histologic findings.
1 citations
,
November 2024 in “Genes” This study suggests that miR-144 influences hair follicle dynamics through its impact on Lhx2, which could lead to advancements in cashmere production, fleece quality, and treatments for hair growth disorders.
1 citations
,
January 2021 in “Arthritis Research & Therapy” The study reported a 7.80% prevalence of scarring alopecia in Chinese SLE patients and identified several risk factors, including mucocutaneous lesions and high disease activity, while renal and cardio-respiratory involvements were negatively associated with it.
This study found clinical markers like leukotrichia and trichrome lesions in non-segmental vitiligo patients were linked to greater disease extent and poor response to treatment.
This review analyzed literature on primary cutaneous lymphomas involving the scalp, finding that scalp involvement in these cases often leads to non-scarring focal alopecia and may indicate more aggressive disease.
February 2025 in “International Journal of Molecular Sciences” In this study using a mouse model, RIPK1 inhibitors were found to delay the onset of alopecia areata, reduce immune cell numbers in affected skin, and increase hair length, indicating a potential therapeutic role in preventing alopecia areata.
September 2009 in “European Urology Supplements” Surgery for high-risk prostate cancer is challenging but doesn't lead to more complications, and additional treatment is often needed.
339 citations
,
February 2014 in “Journal of The American Academy of Dermatology” This study found that eyelash loss, facial papules, and body hair involvement were linked to severe frontal fibrosing alopecia, and antiandrogens were the most effective treatment.
13 citations
,
December 2001 in “Dermatologic therapy” This review discusses the clinical presentations of alopecia areata, introduces guidelines for treatment studies, and explores potential changes in cutaneous innervation, but reports no new clinical results.
3 citations
,
November 2021 in “Frontiers in Medicine” This study found that androgenetic alopecia can affect the occipital region in men with advanced stages of the condition.
2 citations
,
September 2012 in “Pharmaceutical patent analyst” This editorial reviews recent European legal developments related to patents on second medical uses and dosage regimes, with no new research findings reported.
22 citations
,
August 2020 in “Cells” This review discusses the role of TGM3 in skin and hair follicle biology, human tumor pathology, and genetic abnormalities, and reports no novel results; the authors highlight its potential as a cancer diagnostic biomarker.
May 2024 in “Journal of Pakistan Association of Dermatologists” This study observed no statistically significant relationship between vitamin D levels and alopecia areata, including different types of the disease, suggesting vitamin D may not play a central role in its development or extent among a sample of adults.
May 2025 in “Journal of Inflammation Research” This study found that NK and CD8+ T cell infiltration may drive inflammation in androgenetic alopecia, suggesting that targeting IL-15 signaling could offer a new therapeutic approach for hair regeneration.
March 2023 in “Lecture Notes in Education Psychology and Public Media” This analysis found that women preferred men with beards for short-term relationships and clean-shaven men for long-term relationships, while men preferred long-haired women for long-term relationships but had no preference for short-term relationships.
2 citations
,
June 2025 in “Medicina” This retrospective study in pediatric patients with Sjögren's syndrome found consistent indications of tear film instability and identified systemic features like arthralgia, Raynaud's phenomenon, and frequent autoantibody positivity, underscoring the value of integrating clinical and ophthalmological assessments for early diagnosis.
May 2026 in “The Journal of Headache and Pain” In this study, researchers developed an enhanced rodent model of trigeminal neuralgia, demonstrating that structural and functional changes in the anterior cingulate cortex are linked to chronic pain and emotional disturbances, and chemogenetic inhibition of specific neurons could alleviate symptoms.
11 citations
,
July 2022 in “International Journal of Molecular Sciences” This study found that treating reconstructed human epidermis with beta-lipohydroxy salicylic acid increased tight junction remnants in the stratum corneum, potentially affecting skin cohesion and desquamation.
November 2025 in “Annals of Dermatology” This study found a strong positive correlation between alopecia areata burden and the Socio-Demographic Index, indicating a disproportionate impact on high-income countries, especially affecting young adults and females.
9 citations
,
August 2021 in “Biomedicines” This study found that 17β-estradiol was the most powerful hormone for inducing APE1/Ref-1 secretion in cultured vascular endothelial cells, with secretion occurring through exosomes dependent on estrogen receptors and intracellular calcium.
2 citations
,
December 2023 in “International journal of molecular sciences” This study reviews the complex keratinization process in the epidermis, detailing how various factors regulate keratinocyte differentiation and emphasizing the importance of understanding this process for the pathogenesis of skin disorders like ichthyoses and psoriasis.
1 citations
,
July 2024 in “International Journal of Molecular Sciences” In this study, miR-181a was found to inhibit the proliferation and induction abilities of ovine dermal papilla cells by targeting the GNAI2 gene and affecting the Wnt/β-Catenin signaling pathway, highlighting its role in the regulation of hair follicle growth and development.
2 citations
,
July 2024 in “Indian Journal of Dermatology” In this study, researchers found that adults with alopecia areata exhibited trichoscopic features of empty follicular openings and tulip hair, while children showed more honeycomb pigment patterns and pohlpinkus constriction on their scalp lesions.
May 2025 in “International Journal of Women’s Dermatology” In this retrospective cohort study, researchers found that exposure to 5-alpha reductase inhibitors and spironolactone in female alopecia patients was not linked to an increased risk of developing malignant or benign gynecologic tumors when compared to minoxidil use.
9 citations
,
November 2023 in “Supportive Care in Cancer” This study found that breast cancer patients treated with CDK4/6 inhibitors plus endocrine therapy experienced more pronounced vertex hair loss and were less responsive to minoxidil treatment compared to those on endocrine monotherapy.
23 citations
,
October 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This consensus report outlines Brazilian dermatologists' recommendations for treating alopecia areata, highlighting intralesional corticosteroids for localized cases and systemic therapy for extensive, active disease, along with monitoring side effects.
21 citations
,
February 2024 in “JAMA Dermatology” This study identified multiple factors affecting the severity of alopecia areata, suggesting they could inform a tool for measuring disease impact and guide treatment selection.