The Involvement of RIPK1 in Alopecia Areata

    February 2025 in “ International Journal of Molecular Sciences ”
    Hyun-Ju Kim, Mei Zheng, Seungchan An … Jong-Hyuk Sung
    Studysummary In this study using a mouse model, RIPK1 inhibitors were found to delay the onset of alopecia areata, reduce immune cell numbers in affected skin, and increase hair length, indicating a potential therapeutic role in preventing alopecia areata.
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    Research cited in this study 9

    1. Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences International journal of molecular sciences · 2024
    2. CXCL12 Neutralizing Antibody Promotes Hair Growth in Androgenic Alopecia and Alopecia Areata International Journal of Molecular Sciences · 2024
    3. Autophagy Induces Hair Follicle Stem Cell Activation and Hair Follicle Regeneration by Regulating Glycolysis 2024
    4. Functional Interrogation of Lymphocyte Subsets in Alopecia Areata Using Single-Cell RNA Sequencing Proceedings of the National Academy of Sciences · 2023
    5. Selective Inhibition of JAK3 Signaling Is Sufficient to Reverse Alopecia Areata JCI insight · 2021
    6. Immunology of Alopecia Areata Central-European Journal of Immunology/Central European Journal of Immunology · 2020
    7. Hair Growth Promotion by Necrostatin-1s Scientific Reports · 2020
    8. Stimulation of Hair Growth by Small Molecules That Activate Autophagy Cell reports · 2019
    9. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014

    Related research 1

    1. Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child International journal of research in dermatology · 2019