A Modified FLIT-B Model of Trigeminal Neuralgia Reveals Anterior Cingulate Cortex Involvement in Anxiety-Like Behavior in Mice
May 2026
in “
The Journal of Headache and Pain
”
Studysummary In this study, researchers developed an enhanced rodent model of trigeminal neuralgia, demonstrating that structural and functional changes in the anterior cingulate cortex are linked to chronic pain and emotional disturbances, and chemogenetic inhibition of specific neurons could alleviate symptoms.
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