Scalp Involvement in Primary Cutaneous Lymphomas: An Update on Clinical Presentation, Diagnostics, and Management

This review examines the involvement of the scalp in primary cutaneous lymphomas (PCLs), analyzing 1482 patients and identifying 1096 cases of B-cell PCLs and 384 cases of T-cell PCLs. Hair loss, primarily non-scarring focal alopecia, was observed in 69% of patients. The study highlights the importance of recognizing scalp involvement due to the potential aggressiveness of some lymphomas in this area. It notes a male predominance and a mean age of onset in the fifth decade for T-cell lymphomas and the fourth decade for B-cell lymphomas. The document emphasizes the need for thorough physical examinations and the use of trichoscopy to guide biopsies, as well as the importance of psychological support for patients. Early detection is crucial for improving outcomes, although the pathogenesis remains unclear and treatment recommendations are not specifically tailored for scalp PCLs.