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research Kyoto Rhino Rats Derived by ENU Mutagenesis Undergo Congenital Hair Loss and Exhibit Focal Glomerulosclerosis

9 citations , January 2011 in “EXPERIMENTAL ANIMALS”

This study describes a novel hairless mutant rat strain, F344-Hr(krh), developed via ENU mutagenesis, which provides a model for skin disease and potentially focal glomerulosclerosis due to specific genetic mutations.

research Focal Asymptomatic Hair Loss in an Adolescent: A Case Report

December 2019 in “Journal of pediatrics & neonatology”

This case report discusses the diagnosis and management of temporal triangular alopecia in a pediatric patient experiencing asymptomatic hair loss, emphasizing its nonprogressive nature and poor prognosis for regrowth.

research Focal atrichia: A diagnostic clue in female pattern hair loss

2 citations , October 2017 in “Journal of The American Academy of Dermatology”

In this study, focal atrichia was associated with late-onset female pattern hair loss, providing a clinical clue to its diagnosis, particularly separating it from other hair disorders.

research Diagnosis and Treatment of Nonscarring Hair Loss in Primary Care in 2021

4 citations , March 2021 in “JAMA”

This article discusses the evaluation and management of common nonscarring hair loss conditions and reports no new clinical results.

research Hair Loss: Diagnosis and Treatment.

September 2024 in “PubMed”

This source provides an overview of different types of hair loss and their treatments, emphasizing the importance of comprehensive evaluation and patient education in managing conditions like androgenetic alopecia and alopecia areata, to address related psychological impacts and improve quality of life.

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Community Join

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community What if DHT is not the vilan.

13 upvotes 5 years ago

Hair loss may be influenced more by inflammation, microbiome imbalances, and gut health than DHT. Treatments discussed include minoxidil, finasteride, RU58841, fecal microbiota transplants, and JAK inhibitors.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community Hair greed made me switch to Dut too early

in Chat 42 upvotes 1 year ago

The user switched from finasteride to dutasteride for hair loss but faced increased shedding and anxiety, regretting not staying with finasteride longer. Other users shared mixed experiences, advising patience with dutasteride, as it may take up to a year to show results.

community Do not recommend topical finasteride after two years.

117 upvotes 1 month ago

Topical finasteride was ineffective for some users, leading to hair loss, while others found it beneficial. Alternatives like oral finasteride, dutasteride, minoxidil, and combinations with tretinoin and keto shampoo were suggested.

community LLLT product recommendations (that don’t cost thousands of dollars)

in Product 7 upvotes 1 year ago

The conversation discusses affordable low-level light therapy (LLLT) products for hair loss, with users debating the effectiveness of red LEDs versus lasers. The original poster is already using finasteride, minoxidil, ketoconazole, and microneedling, and is seeking budget-friendly LLLT options to add to their regimen.

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Learn

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Hair Transplant

Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.

learn Aminexil

Does it work better in certain areas, like receding hairlines or the crown? Hair loss treatments generally work better on the crown than on receding hairlines.

learn Folic acid

How does folic acid support hair follicle health and growth at a cellular level? Folate is required for the DNA synthesis that fast-dividing hair matrix cells depend on, and severe deficiency causes anemia—but no published trial has given folic acid to people with hair loss and measured the result, so a growth effect is a mechanism, not a finding.

learn Tofacitinib

What are the key limitations and considerations surrounding tofacitinib in hair loss products and therapies? Reported hair regrowth with tofacitinib comes from alopecia areata, an autoimmune condition — mostly from small, non-randomized studies, with relapse common after stopping. There is no good evidence it helps pattern hair loss, and it is not approved for hair loss anywhere.

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.

learn Trichogen® (foligain)

learn PP405

Got small bald patches they say are from stress? PP405 sprays could help bring them back to life. PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.

learn Bimatoprost

a synthetic prostamide used to treat eyelashes also shows promise for stimulating hair growth on scalp

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Clinics

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Hair Systems
Focal Point Salon & Spa @ The Vibe BarPhoenix · US

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