Primary Cutaneous Follicle Centre Cell Lymphoma of the Scalp Presenting with Scarring Alopecia

    March 2011 in “ British Journal of Dermatology
    J. Kluk, R. Charles‐Holmes, Richard Carr
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    Studysummary This report describes a case of primary cutaneous follicle centre cell lymphoma presenting as hair thinning on the scalp, which is not a recognized feature of the condition. Our plain-language summary of this paper — not a Tressless recommendation.
    A 55-year-old woman with a 5-year history of hair thinning and scarring alopecia on the scalp was diagnosed with primary cutaneous follicle centre cell lymphoma (PCFCCL), a condition not typically associated with alopecia. Histological and immunohistochemical analysis confirmed the diagnosis. The patient responded well to superficial radiotherapy, which led to the complete resolution of plaques and some hair regrowth. The study emphasized the importance of biopsy in scarring alopecia cases and suggested exploring newer treatments like intralesional rituximab to reduce scarring and alopecia.
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