Unusual Clinical Presentation of a Primary Cutaneous Follicle Center Lymphoma on the Scalp of a Middle-Aged Female: Case Report and Review of the Literature

    January 2019 in “ Skin appendage disorders ”
    Azhar Ahmed, Hind M. Almohanna, Jacob Griggs, Antonella Tosti
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    TLDR A woman with a rare scalp lymphoma had unusual hair loss after treatment.
    In 2019, a 64-year-old female with a history of primary cutaneous follicle center lymphoma (PCFCL) exhibited an unusual presentation of an atrophic alopecic patch on her scalp where a nodule had regressed after rituximab treatment. This was notable as other nodules had regressed without causing alopecia. The initial diagnosis of PCFCL, a rare indolent lymphoma with a good prognosis, was made in 2016. The document reviewed treatment options for PCFCL, including radiotherapy, surgical excision, systemic rituximab, and other therapies, while noting their varying success rates and potential for causing alopecia. A retrospective analysis of 14 patients with scalp PCFCL showed diverse outcomes, and cases of PCFCL presenting with both scarring and nonscarring alopecia were mentioned, highlighting the need for accurate diagnosis through histopathology and immunohistochemistry.
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