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Lower proximal cup cells, not bulge stem cells, regenerate hair follicles after chemotherapy.

Certain cells outside the hair follicle's bulge area can quickly regenerate damaged hair follicles, potentially helping to reduce hair loss from cancer treatments.

Hair follicles repair 3D injuries using a 2D healing process.

Wnt-signaling is regulated differently in skin cells and immune responses during wound healing.

Mouse skin glands need healthy nerves to grow properly during hair growth phases.

Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.

Cold atmospheric plasma may speed up wound healing and control infections.

Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.

Combining platelet-rich plasma injections and gel may effectively treat morphea, improving skin elasticity and reducing pain.

CD4+ skin cells may be precursors to basal cell carcinoma.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Dogs could be good models for studying human hair growth and hair loss.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

Different small areas within hair follicles send specific signals that control what type of cells stem cells become.

Vitamin D Receptor is crucial for hair follicle shrinkage and cell death, affecting hair growth.

SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

Dermal stem cells help regenerate hair follicles and heal skin wounds.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.