Hair Follicles Employ a Two-Dimensional Healing Strategy to Repair Three-Dimensional Injuries
September 2019
in “
The journal of investigative dermatology/Journal of investigative dermatology
”
hair follicles anagen hair follicle repair radiation-induced damage germinative cells matrix cells apoptotic basal outer root sheath cells lower proximal cup cells multiphoton intravital imaging cell regeneration 3-dimensional injuries 2-dimensional healing mathematical modeling AHFR radiation damage cell death outer root sheath cells proximal cup cells cell imaging cell repair 3D injuries 2D healing modeling
Studysummary In this study, the researchers observed that post-radiation hair follicle repair in 3D architecture occurs through independent, long-range cell movements along the basal surface, resembling 2D healing processes.
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