September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, the researchers observed that post-radiation hair follicle repair in 3D architecture occurs through independent, long-range cell movements along the basal surface, resembling 2D healing processes.
4 citations
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January 2016 in “Methods in molecular biology” This study found that hair-follicle-associated pluripotent stem cells can promote nerve repair and growth in a 3D culture model and potentially differentiate into cardiac muscle cells, offering advantages over other stem cell types for regenerative medicine.
June 2026 in “Nano Research” In this study, researchers developed a novel 3D bio-printed skin scaffold using exosomes from liver cells, which enhanced wound healing by promoting cell growth, angiogenesis, and reducing inflammation in large skin injuries, suggesting potential applications in treating chronic skin conditions.
32 citations
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January 2014 in “Cells tissues organs” This study reports that hair follicle stem cells, termed HAP stem cells, can differentiate into neuronal and glial cells, enhancing nerve repair and locomotor recovery after injury.
November 2024 in “Burns & Trauma” This review examines how skin organoids, derived from stem cells, are constructed to simulate skin functions and are pivotal in wound healing and regeneration, highlighting their promising roles in both research and therapeutic applications.
