research High-Performance Liquid Chromatographic Method for the Determination of Finasteride in Human Plasma at Therapeutic Doses
Reliable method detects finasteride in human plasma at low doses.
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research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia
Androgens, like DHT, affect hair growth and treatments like finasteride may help.
research Finasteride: A Slow-Binding 5-Alpha-Reductase Inhibitor
Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.
research Three Isostructural Solvates of Finasteride and Their Solid-State Characterization
Three new finasteride solvates found, change forms under different drying conditions.
![Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2](/images/research/efc54340-66d6-4f27-9930-045ac023f903/small/15248.jpg)
research Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2
New compounds were made that effectively block enzymes related to prostate issues and hair loss.
research Picogram Determination of Finasteride in Human Plasma and Semen by High-Performance Liquid Chromatography with Atmospheric-Pressure Chemical-Ionization Tandem Mass Spectrometry
Method detects finasteride in plasma and semen with high sensitivity and accuracy.
research Platelet-Rich Fibrin Matrix for Androgenetic Alopecia
PRFM may help treat hair loss, especially in mild cases.
research A Connection Between the Mitochondrial Permeability Transition Pore, Autophagy, and Cerebral Amyloidogenesis
Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.
research Quality Evaluation of the Finasteride Polymorphic Forms I and II in Capsules
Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.
research Phenomenology of Polymorphism: The Topological Pressure–Temperature Phase Relationships of the Dimorphism of Finasteride
Finasteride's two forms have different stability based on temperature and pressure.
research Microbial Oxidation of Finasteride with Macrophomina Phaseolina (KUCC 730)
research Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus Acutissima Cortex
An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
research Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity
Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.
research Anti-Androgens for the Treatment of Hirsutism
Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.
research Separation of Finasteride and Analogues
Finasteride and analogues separated using LC-MS-MS technique.
research Selective Induction of Apoptosis in the Hamster Flank Sebaceous Gland Organ by a Topical Liposome 5-Alpha-Reductase Inhibitor: A Treatment Strategy for Acne
A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
research Pharmacological Options for Treatment of Hyperandrogenic Disorders
Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
research Clinical Use of 5α-Reductase Inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
research Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia
Finasteride doesn't effectively treat hair loss in postmenopausal women.
research Effects of Flutamide and Finasteride on Rat Testicular Descent
Androgens, like testosterone, are crucial for early testicular descent in rats.
research Hair Growth and Rejuvenation: An Overview
The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.
research Comparative Efficacy of Various Treatment Regimens for Androgenetic Alopecia in Men
Best hair growth results from combining finasteride and minoxidil.
research Inhibition of Skin 5α-Reductase by Oral Contraceptive Progestins In Vitro
Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.
research Structural Study of Polymorphs and Solvates of Finasteride
Different forms of hair loss drug can improve effectiveness.
research A Prospective Randomized Trial Comparing Finasteride to Spironolactone in the Treatment of Hirsute Women
Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.
research Clinical Dose Ranging Studies with Finasteride, a Type 2 5α-Reductase Inhibitor, in Men with Male Pattern Hair Loss
Finasteride effectively treats male pattern hair loss with a 1 mg daily dose.
research Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia
Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
research Finasteride, a Type 2 5α-Reductase Inhibitor, in the Treatment of Men with Androgenetic Alopecia
Finasteride effectively treats male hair loss, improving growth and density.
research Finasteride Induced Gynecomastia: Case Report and Review of the Literature
Finasteride for hair loss may cause gynecomastia; doctors should inform patients.
research Treatment of Hirsutism with 5α-Reductase Inhibitors
New compounds may soon be tested to treat excessive hair growth in women.