January 2024 in “Journal of Education, Health and Sport” More research is needed to fully understand the benefits of platelet-rich plasma in medicine.
Platelet-rich plasma injections effectively increase hair density in men suffering from common hair loss.
January 2022 in “Pastic and aesthetic research” PRP helps skin regeneration but needs standardized testing for consistent results.
February 2020 in “International Journal of Research in Dermatology” Platelet rich plasma is not proven as a treatment for hair loss despite some improvements.
The study demonstrated that platelet-rich plasma (PRP) significantly promoted the viability and proliferation of human hair dermal papilla cells (HHDPCs) in vitro, particularly at a 5% concentration. PRP also increased the expression of alkaline phosphatase (ALP) and versican at both mRNA and protein levels. The study involved 8 healthy volunteers and used MTT assays, qRT-PCR, and Western blot analysis. These findings suggested that PRP could be a potential therapeutic tool for promoting hair follicle regeneration and treating alopecia, although further research is needed to identify the specific growth factors responsible for these effects.
May 2015 in “Hair transplant forum international” The article concludes that PRP might help with hair loss, but more detailed research is necessary.
January 2022 in “International Journal of Trichology” The study evaluated the efficacy of minoxidil, platelet-rich plasma (PRP) therapy, and their combination in treating androgenetic alopecia (AGA) in 69 men. Participants were divided into three groups: 25 received both minoxidil and PRP, 22 received only PRP, and 22 received only minoxidil. Results showed that the combination therapy significantly improved hair density by 32%, hair shaft diameter by 26%, reduced vellus hair by 30%, and decreased telogen hair by 39%, outperforming the monotherapies. The findings suggest that PRP and minoxidil enhance each other's effects, making their combined use a promising treatment for AGA.
December 2020 in “Aktualʹnì problemi sučasnoï medicini” The study compared the efficacy of betamethasone injections, platelet-rich plasma (PRP) injections, and their combination in treating alopecia areata in 104 patients with an average age of 35.7 years. Patients were randomly divided into three groups: one received betamethasone injections monthly, the second received PRP injections bi-weekly for 16 weeks, and the third received alternating treatments of betamethasone and PRP. Observations were made before treatment and at 3, 6, and 17 months post-treatment. The results indicated that the combination therapy yielded the best outcomes, particularly in long-term follow-ups.
January 2020 in “International Journal of Trichology” This case report described a 58-year-old male with temporal triangular alopecia (TTA) treated with platelet-rich plasma (PRP) injections. The treatment involved 5 monthly sessions of 2 ml PRP injections. Dermoscopic follow-up showed an increase in the number and thickness of vellus hairs, but the overall clinical improvement was unsatisfactory, with hair thinning recurring 6 months after treatment discontinuation. The study concluded that PRP might not be a suitable treatment for TTA due to its transient response and limited efficacy. Further research was recommended to explore better treatment options for TTA.
December 2018 in “Вестник Российской Военно-медицинской академии” The study investigated the clinical efficacy of platelet-rich plasma (PRP) in treating 22 men with androgenic alopecia. Patients received intradermal PRP injections over 4 sessions at 4-week intervals. Results showed significant improvements: hair density increased by 11%, average hair diameter by 10%, and a 14% decrease in the proportion of vellus hair. Histological analysis revealed a 148% increase in hair follicle density at the bulb level and a 65% increase at the sweat gland level. Additionally, there was a 47% reduction in telogen hair. These findings indicated that PRP therapy led to significant morphofunctional changes in hair follicles, supporting its clinical efficacy in treating androgenic alopecia.
May 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” 16 citations,
December 2019 in “Journal of Cellular and Molecular Medicine” Sonicated platelet-rich plasma boosts hair growth by activating stem cells.
31 citations,
April 2018 in “Plastic and Reconstructive Surgery” PRP therapy may improve skin and hair conditions, but more research with standard methods is needed.
January 2015 in “Surgical and Cosmetic Dermatology” Platelet-rich plasma injections are an effective treatment for hair loss with minimal side effects.
62 citations,
October 2016 in “Dermatologic Therapy” PRP more effective than minoxidil 5% for treating alopecia areata.
1 citations,
November 2021 in “European journal of medical and health sciences” Growth factors-rich plasma treatments can significantly speed up wound healing and tissue regeneration.
November 2023 in “Periodontology 2000” Injectable platelet-rich fibrin has improved healing and regeneration in various medical fields and can be more effective than previous treatments.
3 citations,
October 2021 in “Dermatologic Therapy” The study compared the effectiveness of platelet-rich plasma (PRP) application using dermapen microneedling and intradermal point-by-point injection methods in patients with androgenetic alopecia. Clinical findings and Trichoscan analysis were used to evaluate the outcomes. The results indicated that both methods significantly improved hair density and thickness, but the dermapen microneedling method showed slightly better results in terms of patient satisfaction and hair regrowth. The study suggests that PRP application, particularly through microneedling, can be a promising treatment for androgenetic alopecia.
May 2022 in “Journal of advances in medicine and medical research” Adding PRP to hair transplants improves treatment for cicatricial alopecia.
31 citations,
July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.
22 citations,
August 2017 in “Stem cells and cloning” Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.
14 citations,
July 2021 in “Biomedicines” Platelet-rich treatments can help improve wound healing and tissue repair.
October 2023 in “Recima21” Platelet-rich plasma treatment is effective for increasing hair thickness and works well for hair density in men with androgenetic alopecia.
PRP is a versatile and affordable treatment for improving appearance in the elderly, with patient needs and expectations being important.
January 2022 in “Springer eBooks” Platelet-rich plasma (PRP) is a promising treatment for hair loss, believed to extend the life cycle of hair follicles and prevent their shrinkage.
March 2017 in “Open access journal of surgery” The document concludes that more standardized research is needed to fully understand and optimize the use of platelet-rich fibrin in regenerative medicine.
66 citations,
June 2015 in “Aesthetic Plastic Surgery” Platelet preparations generally show positive effects on wound healing and facial rejuvenation, but more thorough research is needed to confirm their effectiveness.
11 citations,
June 2020 in “Dermatologic Therapy” PRP treatment improves hair density and diameter in women with androgenetic alopecia.
3 citations,
January 2016 in “International Journal of Research in Medical Sciences” Using both minoxidil and platelet-rich plasma therapy together is more effective for hair growth in women than using minoxidil alone.
December 2019 in “Medicina estética/Medicina estética” PRP may help improve hair transplant results.