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This study in adult male albino rats reported that human umbilical cord blood-derived mesenchymal stem cells were more effective than minoxidil in promoting hair growth for androgenic alopecia, observing superior outcomes in hair follicle metrics.

In this study, secretomes from hypoxic mesenchymal stem cells were found to increase PDGF and reduce IL-1β gene expression in rats, potentially offering an effective topical treatment for alopecia caused by long-term fluconazole use.

This study found that exosomes derived from human bone marrow mesenchymal stem cells significantly promote cutaneous wound healing in rats by modulating the TGF-β/Smad signaling pathway.

This review discusses the use of mesenchymal stem cells in treating diseases, particularly focusing on their application in pediatric Graft-versus-Host Disease, with most studies reporting safety and effectiveness in animals.

Modified stem cells can improve hair growth.

This review suggests that omitting the proteolysis step and including tissue pieces in mesenchymal stem cell isolation may improve cell quality, reduce contamination risk, and lower costs and processing time in clinical applications.

This study found that adipose-derived mesenchymal stromal cell secretome, particularly when preconditioned with IFNγ, significantly influences cell motility and anti-inflammatory responses, enhancing its potential as a regenerative therapy.

This study found that the postnatal thymus contains a population of mesenchymal stem cells that may help maintain functional thymic microenvironments.

In this study, MSC-scaffold combinations were found to significantly enhance wound closure, collagen deposition, angiogenesis, and growth factor expression while modulating inflammatory responses in preclinical burn wound models, though significant heterogeneity limits immediate clinical application.

This study found that mesenchymal stem cells derived from dental pulp and adipose tissue have distinct gene expression signatures that suggest potential target diseases for clinical applications.

This article reviews the use of mesenchymal stem cells and biomimetic scaffolds in regenerative medicine, highlighting promising in vitro and in vivo outcomes, but it reports no new clinical results.

This study found that combining adipose-derived mesenchymal stem cells with platelet-rich plasma improved key healing markers in bowel anastomoses in rats with induced colitis, suggesting potential benefits for anastomosis recovery even in inflamed conditions.

This paper proposes a model integrating regulatory T cells and mesenchymal stem/stromal cells to enhance understanding of peripheral immune tolerance, suggesting their combined roles in immune regulation, autoimmunity pathophysiology, and potential MSC-based therapies.

This study developed a molecular systems architecture to map the complex interactions between mesenchymal stromal cells and their microenvironment, providing a framework for future predictive models that could enhance therapeutic strategies and reduce adverse effects.

In this study, human gingival mesenchymal stem cells responded differently to inflammation mediated by oxidized low-density lipoprotein (oxLDL) compared to cytokines; oxLDL significantly reduced cell proliferation but had less negative impact on differentiation characteristics.

In this review, it is discussed how mesenchymal stem cell aggregation plays a crucial role in organ development and has potential applications in organ regeneration through tissue engineering.

This study observed that MRI treatment increased expression of stemness-related genes and colony formation in umbilical cord-derived mesenchymal stem cells without affecting viability or apoptosis, suggesting enhanced quality for therapeutic use.

This review outlines recent advances in stem cell and tissue engineering technologies in regenerative medicine and wildlife conservation, reporting no new clinical results.

This review discusses the role of extracellular vesicles in wound healing and explores their potential applications in skin repair and treatment of dermal diseases, reporting no new clinical findings.

This review examines mesenchymal stem cell therapy as a promising alternative for end-stage liver disease, discussing completed clinical trials and highlighting challenges that must be addressed before clinical application.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

This review discusses the potential benefits and biological activities of MSC secretome for various skin applications, but it reports no new clinical results.

This meta-analysis suggests that stem cell therapy may reduce burn wound area and improve healing-related factors in preclinical models, indicating potential for future clinical studies on burn treatment.

The authors reported that a combination of amino acid and stem cell therapy may have extended survival in a dog with hepatocutaneous syndrome to 32 months post-diagnosis.

This overview highlights the exploration of mesenchymal stromal cells as potential treatments for COVID-19, noting their regenerative and immunomodulatory properties for reducing ARDS severity in critically ill patients, but it provides no new clinical results.

This study found that treating acute and chronic canine skin wounds with adipose-derived mesenchymal stem cells significantly improved healing and reduced inflammation, suggesting potential benefits for human wound care.

This review assessed the potential of mesenchymal stem cell therapy to enhance burn wound healing, highlighting its capabilities in promoting angiogenesis, reducing inflammation, and regenerating damaged tissues, while identifying preclinical and clinical challenges that need addressing to optimize treatment outcomes.

In this study, an immortalized MSC line from human adipose tissue showed potential for applications in regenerative medicine and inflammatory diseases through production of active factors, demonstrated in vitro.

In this study, a peptide hydrogel scaffold loaded with umbilical cord-derived mesenchymal stem cells was used to repair damaged endometrium in rats, significantly improving fertility and live birth rates by restoring endometrial thickness and promoting angiogenesis.

This review discusses the interaction between mesenchymal stem cell secretomes and retinal cell secretomes, suggesting their potential in experimental therapies to protect and regenerate retinal tissue.