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Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.

Dermal papilla cells can help regrow hair and are promising for hair loss treatments.

Higher GPER-1 levels are linked to more severe and shorter-duration androgenetic alopecia, suggesting GPER-1 as a potential treatment target.

Mitochondrial dysfunction links metabolic syndrome and inflammatory skin diseases, suggesting targeted therapies and lifestyle changes.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Genes linked to wool fineness in sheep have been identified.

Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.

Terminalia bellirica extract may help promote hair growth and prevent hair loss caused by testosterone.

New understanding and treatments for hair loss are improving, but more research is needed.

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

Insulin resistance increases the risk of developing type 2 diabetes and other health issues.

Too much prolactin can cause menstrual problems, infertility, and sexual issues in women.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Protein profiling of forehead skin can help distinguish between frontal fibrosing alopecia and androgenetic alopecia.

Targeting CXXC5 and GSK-3β may help treat male pattern baldness.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Androgens can help prevent memory problems caused by apoE4.

Finasteride may improve prostate cancer treatment outcomes.

Dutasteride and finasteride affect different cell types differently.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

A new topical solution safely reduces hair shedding by 38% on average by tightening a muscle in the scalp.