Prolactin and Hyperprolactinemia in Female Reproductive Endocrinology – An Update

    February 2021 in “ Facta Universitatis ”
    Ranko Kutlešić, Jasmina Popović, Milan Stefanović, Predrag Vukomanović, Ranko Kutlešić, Danka Mostić Stanišić
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    TLDR Too much prolactin can cause menstrual problems, infertility, and sexual issues in women.
    The document discusses the significant role of prolactin, a hormone, in physiological processes such as lactation and reproduction. It also explores the health issues caused by hyperprolactinemia, an excess of prolactin in the blood, which include menstrual irregularities, infertility, and sexual dysfunction. The impact of hyperprolactinemia on conditions like polycystic ovary syndrome and endometriosis is also discussed. The document emphasizes the importance of accurate diagnosis and effective management of hyperprolactinemia, which can be complicated due to factors like the 'hook effect' that can result in falsely low serum prolactin readings in cases of invasive macroprolactinomas. It also mentions the prevalence and clinical significance of macroprolactinemia, a condition characterized by high levels of macroprolactin, in patients with prolactinomas.
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      community does lowering your prolactin levels regrow hair?

      in Research/Science  10 upvotes 1 year ago
      The potential of lowering prolactin levels to regrow hair, with a reference to Bayer's drug HMI 115 which has been indicated as having this effect. Treatments mentioned include Minoxidil and Finasteride, as well as RU58841.

      community how about progesterone cream?

      in Research/Science  23 upvotes 7 months ago
      Progesterone cream might help with hair loss by inhibiting DHT production and suppressing prolactin, which can increase DHT. Some dermatologists have used progesterone for hair loss treatment, and it has been effective, sometimes combined with minoxidil, finasteride, and hydrocortisone.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community hmi115 is coming. Prepare yourselves for what's coming

      in Technology  104 upvotes 1 year ago
      The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

      community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

      in Update  35 upvotes 5 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

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