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The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.

Minoxidil promotes hair growth by penetrating skin, with ethanol-containing formulas working best.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.

Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.

Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

Hair follicles help substances penetrate the skin faster and more effectively.

TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.

Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.

Effective sunscreen formulations can reduce skin absorption and enhance protection.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Chitosan microparticles improve minoxidil sulphate delivery, potentially reducing daily applications.

Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.

Targeting hair follicles can improve skin treatments and reduce side effects.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

The document suggests that the traditional understanding of hair growth cycles and alopecia may be inaccurate and that blood supply plays a significant role in hair growth and loss.

Iontophoresis improves minoxidil delivery for alopecia treatment.

Nanotechnology could make hair loss treatments more effective and reduce side effects, but more research is needed before it's available.

Ultrasound is a useful, non-invasive tool in dermatology for diagnosing skin conditions and guiding treatments, but it has some limitations.