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This study outlines trichodynia, a painful scalp condition often linked with various types of alopecia and psychiatric disorders, noting the absence of specific treatments and highlighting the need for further research on therapeutic options.

In this study, chronic finasteride administration in male rats led to depression- and anxiety-like behaviors only in specific tests and moderately affected hippocampal synaptic plasticity, possibly due to adaptive plasma corticosterone level changes over time.

This article reviews the causes and current treatment options for androgenetic alopecia, reporting no new clinical findings and highlighting the need for more therapeutic choices.

In this study, researchers using a multi-omics approach identified specific proteins involved in the hair follicle cycle of Inner Mongolia Cashmere Goats, finding that API5 affects apoptosis, while ribosomal proteins are highly expressed during the resting stage, providing insights into hair follicle growth and apoptosis.

In this study on mice with severe thermal skin burns, researchers found that administering 4-aminopyridine (4-AP) helped reduce inflammation and apoptosis, promoted angiogenesis, and accelerated wound healing by enhancing specific cellular behaviors and signaling pathways.

This study found that AIRE, a usually nuclear protein, is expressed in the cytoplasm of human epidermal and follicular keratinocytes and associates with the intermediate filament protein cytokeratin 17, potentially impacting ectodermal abnormalities in APECED syndrome.

This study found that loss of Apc due to K14-cre-mediated gene recombination in mice led to aberrant growth in ectodermally derived squamous epithelia, implicating its critical role in specifying epithelial cell fates during embryonic development.

A certain gene variation can affect protein production and is linked to male pattern baldness.

KAP genes are crucial for hair development and show both shared and unique traits in humans, chimpanzees, and baboons.

In this study, overexpression of YAP1 was found to promote adipogenic differentiation of goat adipose-derived mesenchymal stem cells by up-regulating LATS2 expression and activating the Hippo pathway's negative feedback loop.

This case report describes a 4-year-old boy with congenital alopecia characterized by complete irreversible hair loss and papular lesions associated with keratin-filled cysts.

In this case report, a novel missense mutation c.1360G>C (p.Ala454Pro) in the MBTPS2 gene was identified in a boy with typical IFAP syndrome and severe atopic features, although no phenotype/genotype correlation was established.

This study found that AP collagen peptides can promote hair growth by supporting the health of hair follicle cells, as they stimulate cell proliferation, counteract apoptosis, and enhance antioxidant enzyme expression, suggesting potential as a treatment for hair loss.

This paper reports on five cases of alopecia areata in children and emphasizes the importance of understanding its characteristics for accurate diagnosis in pediatric patients.

This review summarizes existing evidence on how YAP and TAZ proteins are activated in epidermal keratinocytes and their role in coordinating with other signaling molecules to control transcription and influence epidermal cell fate, highlighting their importance beyond the Hippo pathway.

This study found that inhibiting AP-1 activity in mice modified tumor development, leading to transdifferentiation between squamous and sebaceous tumors, with molecular analysis suggesting AP-1's role in maintaining tumor cell identity.

In this case report, a 67-year-old Thai woman exhibited isolated cheilitis due to actinic prurigo—an unusual presentation in Asian patients—successfully treated with topical hydrocortisone and sun protection, highlighting the need to consider actinic prurigo in chronic lip lesion diagnoses even with normal phototesting results.

This study found that water fractions of Angiopteris evecta stimulated hair growth in male rabbits, suggesting potential alopecia treatment benefits pending further research in humans.

This study isolated a bioactive peptide from Trapa japonica fruit and found that it may protect human dermal papilla cells from DHT-induced stress, suggesting potential for biomedical applications.

Genetic testing for hairless gene mutations is crucial to correctly diagnose and treat atrichia with papular lesions.

This report presents a case of IFAP syndrome with the typical symptoms of alopecia universalis, severe photophobia, and follicular ichthyosis, but provides no additional clinical findings or conclusions.

This case report describes a 3-year-old boy with atrichia with papular lesions, emphasizing that dermoscopy, showing the 'cluster of stars' appearance, facilitated diagnosis without needing a skin biopsy.

In this study, researchers developed a dissolvable microneedle patch containing baricitinib for alopecia areata treatment, reporting significantly higher hair growth in mouse models compared to controls, suggesting its potential as an effective, pain-free topical therapy.

This study found that among an Asian population with alopecia areata, commonly first episodes occurred before age 40, with severe cases linked to psychological effects and treatments showing significant regrowth.

This study found that YAP1 localization and expression patterns in human skin xenografts resembled pathological conditions, suggesting that YAP1 may be a potential target for treating skin pathologies.

In this report, a 2-year-old male with GAPO syndrome exhibited androgenetic-like alopecia with normal testosterone levels and telogen hair loss, which are novel findings for this condition.

This review discusses the roles of the Agouti and Agouti-related proteins in pigmentation and energy regulation and reports no new experimental findings.

This review discussed the cutaneous manifestations of APECED, highlighting chronic mucocutaneous candidiasis, alopecia areata, and vitiligo, while emphasizing the importance of early detection and monitoring for accurate diagnosis and patient care in various populations.

This study found that sheep possess a polymorphic KAP8-2 gene that shares high sequence identity with the KAP8-2 gene in goats and reindeer.

This study in Italy found that APS-1, a rare disorder, is associated with various AIRE gene mutations and most individuals have autoantibodies such as IFNωAbs, which are markers of the condition.