Combining Multiomics to Analyze the Molecular Mechanism of Hair Follicle Cycle Change in Cashmere Goats from Inner Mongolia

This study explores the molecular mechanisms of hair follicle cycle changes in Inner Mongolian cashmere goats using multi-omics analysis, involving nine goats. Researchers identified specific proteins expressed during different hair follicle phases and highlighted the role of apoptosis in these cycles. Apoptosis Inhibitor 5 (API5) was found to significantly influence protein and gene expression, affecting hair follicle apoptosis, while ribosomal proteins were crucial during the resting stage. The study suggests that API5 and ribosomal proteins could serve as molecular markers for hair follicle growth and apoptosis, providing a theoretical basis for further research on cashmere goat hair follicle development.