Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that endothelial TLR2 is crucial for effective angiogenesis and timely wound healing, whereas TLR2 in hair follicle stem cells is not essential for skin regeneration.

This study found that conditioned medium from hair dermal papilla cells stimulated fetal bovine aortic endothelial cell growth and migration, suggesting VEGF-like activity in the medium.

This study found that mesenchymal stem cells sourced from hair follicle outer root sheath showed higher differentiation efficiency and angiogenic potential for vascular graft applications compared to adipose-derived stem cells.

This review explores the potential link between psoriasis and metabolic syndrome, focusing on how disturbances in growth factors may connect these conditions and contribute to symptoms like keratinocyte proliferation and inflammation.

This review reports that chitosan, a versatile polysaccharide, shows potential for various therapeutic applications due to its chemical modifications, notably in treating non-communicable diseases and wound healing, though further clinical study is needed to confirm these benefits.

This review discusses the role of the ectodysplasin A2 receptor as a biomarker and driver of ageing related to inflammation, and its potential therapeutic implications, but reports no new clinical findings.

This review explores the roles of dermal sheath cells in wound healing, highlighting their multifunctional contributions to inflammation, proliferation, and extracellular matrix remodeling, and proposes new insights into tissue regeneration and repair, especially in differentiating between hairy and non-hairy skin sites.

This study reported that newly developed RADA16-I peptide hybrids, with active motifs like GHK and KGHK, demonstrated improved wound healing in a mouse skin injury model without cytotoxicity, suggesting they might be effective scaffolds for tissue engineering and regeneration.

This review highlights cellulose-based materials' potential in skin disease treatments, emphasizing their smart, responsive design for various conditions, with insights into their roles in wound healing, infection prevention, and wearable monitoring.

This study investigated the secretome of adipose mesenchymal stem cells and fibroblasts used in skin care products, finding 16 therapeutic pathways involving numerous signaling mechanisms, which may offer skin benefits through anti-inflammatory and regenerative effects.

This study provides a comprehensive overview of human umbilical cord mesenchymal stem cell-derived extracellular vesicles (HUCMSC-EVs), suggesting their potential to combat aging and alleviate age-related disorders by rejuvenating multiple organs in animal models and discussing engineering strategies to harness their full anti-aging potential.

This study highlights the transformation in aortic aneurysm treatment over the last 30 years, noting the shift from open surgery to endovascular methods, which reduce surgical risks and improve outcomes.

This study found that NNAT is localized in both undifferentiated and differentiated cells across various rat tissues and has cell-specific intracellular localization, suggesting distinct functional roles.

This chapter reviews existing knowledge about melatonin's MT₁ and MT₂ receptors in human tissues, discussing their established and potential functions, but reports no new clinical findings.

In this study, minoxidil treatment in aged mice increased elastin expression and improved aortic structure and function, suggesting its potential for arterial remodeling in aging.

This case study suggests that obstructive sleep apnea syndrome may be hereditary in patients with connective tissue disorders due to a variant in the COL1A2 gene.

This preclinical study found that Mesenchymal Stem Cell-derived Conditioned Media formulations were safe and effective in rat and mouse models for treating chemotherapy- and radiation-induced oral mucositis, demonstrating improved tissue regeneration and healing, most notably at higher concentrations.

In this study, CD34-positive progenitor cells in irradiated salivary glands were observed to potentially aid in blood vessel formation and remodeling, suggesting their role in tissue healing after radiotherapy.

This study suggests that mammalian hair follicles may serve as a viable and non-invasive system for diagnosing traumatic brain injury, reflecting similar molecular responses observed in other tissues.

In this study, researchers found that specific mutations in iRhom2 in mice lead to skin and hair abnormalities which depend on the presence of the protein ADAM17, suggesting a complex role for iRhom2 in tissue development and potential implications for treating tylosis with oesophageal cancer.

This study found that a bioactive borosilicate glass containing Sr and Cu ions exhibited promising mechanical strength, biocompatibility, and antibacterial activity, particularly the CuSr-1 wt.% composition, suggesting potential for use in orthopedic implants and bone tissue engineering.

This review highlights that incorporating nanomaterials into scaffolds can significantly enhance angiogenesis in tissue regeneration by simulating extracellular matrix structures and effectively delivering angiogenesis-related factors, offering promising designs for vascularization and therapeutic applications.

In this review, researchers summarize the methods for characterizing telocytes, outline their physiological roles and implications in diseases, and discuss potential future studies including precise markers and targeted therapies.

This case report highlights that early recognition and management of underlying connective tissue diseases, such as lupus, are essential in young patients presenting with unexpected symptoms like blurry vision and stroke signs.

This review highlights how diabetes affects stem and progenitor cells through altered signaling and homeostasis, impacting tissue function and complicating diabetic therapy efforts; new clinical results are not presented.

This article discusses the role of suction-assisted lipectomy (SAL) and the hCG method in obesity management, highlighting the speculative benefits of hCG but reporting no new clinical findings.

This study identified that bone marrow-derived CD34⁺ cells act as fibroblast progenitors to enhance tissue regeneration in ischemic limbs by promoting angiogenesis through interactions with macrophages.

In this study, chitosan-modified fucoidan/polyethylene oxide nanofibers were developed, showing promise as bio-scaffolds for tissue-engineered blood vessels by enhancing endothelial cell adhesion and inhibiting monocyte attachment.

This study found that injecting blood plasma enriched with platelet growth factors significantly improved the healing and auditory function in patients with acute post-traumatic tympanic membrane perforation compared to natural regeneration.

This study found that mechanical skin stretching can stimulate hair stem cell proliferation and hair regeneration by activating a complex pathway involving WNT, BMP-2, and M2 macrophages.