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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Low-dose oral minoxidil effectively reduces hair loss in women with female pattern hair loss.

Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Testosterone is crucial for development, growth, and various body functions in mammals.

Ovarian steroid cell tumors should be considered in adults with hirsutism and high testosterone, with surgery as the main treatment.

Scientists have found specific genes linked to different hair loss conditions, which could lead to new treatments.

Some types of hair loss can be reversed, others are permanent, and treatments vary by type.

Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

Finasteride effectively reduces hair loss by decreasing androgen levels.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

Testosterone may slow down wound healing and increase inflammation.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

A patient with a larger than usual genetic mutation had a broader range of symptoms for a muscle disease.

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

Hormonal therapies help treat female hair loss, but results are slow and vary.

Guava leaf extract may help treat hair loss and protect cells by blocking certain genes and fighting damaging molecules.

The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Dermal papilla cells are key for hair growth and could help us understand and treat hair loss.