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Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Human keratinocytes do not naturally respond to androgens.

Metformin works better for adolescent girls with PCOS who have certain genetic variations.

Blocking testosterone speeds up wound healing in males.

Male pattern baldness is linked to higher levels of a certain receptor in the scalp, which leads to the shrinking of blood vessels and hair loss. Early treatment targeting this receptor could be more effective.

Merremia peltata leaf extract, particularly the bufotalinin compound, shows potential for treating hair loss.

Platelet factor 4 slows down hair growth and could make hair loss treatments more effective if removed.

A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.

Chromosomal differences affect how muscle cells respond to testosterone.

A new compound, 3a, effectively fights prostate cancer better than finasteride.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.

New treatments for cancer and skin disorders show promise in disrupting harmful cell interactions and promoting hair growth.

Sebocytes play a key role in controlling androgen levels in human skin.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

New genes and pathways are important for testosterone production and male sexual development.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.

The mouse models are effective for testing new hair loss treatments.

The research found that androgens help control blood flow in the rat prostate through a specific binding site.