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Adult acne is often related to hormonal disorders, especially in women, and may need long-term treatment involving specialists.

Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

The androgen receptor gene doesn't affect women with recurrent spontaneous abortions, but having a mutant genotype might protect against it.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.

COVID-19 may worsen with androgens; anti-androgen drugs could help.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Hair loss may link to weaker COVID-19 immunity, suggesting possible need for extra vaccine boost.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Men with higher androgen levels may have severe COVID-19 symptoms, but those on antiandrogen therapy are less likely to contract the virus and have milder symptoms. Anti-androgen drugs could potentially treat COVID-19, but more research is needed.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Chicken egg yolk peptides can promote hair growth by increasing a specific growth factor.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Glioblastoma cells can make androgens, which might help the tumor grow.

Allopregnanolone changes gene expression in glioblastoma cells.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

PCOS is common, affects fertility, and requires personalized treatment to manage symptoms and health risks.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

Male pattern baldness does not cause an increased risk of prostate cancer.

Cannabidiol shows promise as an effective treatment for acne.

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.