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Gene variation affects prostate issues and hair loss.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Minoxidil can reduce functions related to androgen receptors.

Blocking testosterone speeds up wound healing in males.

Blocking testosterone speeds up wound healing in males.

No significant link between CAG repeat numbers and female pattern hair loss in Han Chinese population.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.

KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Lowering testosterone speeds up wound healing in male mice.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

AR gene not major factor in female hair loss; different from male hair loss.

Women with hair loss have more androgen receptors in certain hair follicles.

The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

The conclusion is that a treatment called cp-asiAR can reduce hair loss and promote hair growth, making it a potential new therapy for androgenetic alopecia.

Dexamethasone increases androgen receptor activity in scalp cells, which might explain stress-related hair loss.

cp-asiAR may effectively treat hair loss by targeting androgen receptors.

Higher levels of heat shock protein 27 and lower levels of miR-1 can increase AR levels, leading to hair loss in men.

The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

cp-asiAR may effectively treat androgenetic alopecia by promoting hair growth and reducing androgen receptor activity.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

Gene differences found in hair follicles linked to male baldness.