research Functional Enhancers as Master Regulators of Tissue-Specific Gene Regulation and Cancer Development
Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.
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research Increased DHT Levels in Androgenic Alopecia Selected to Protect Men from Prostate Cancer
Higher DHT in male baldness may protect against prostate cancer.
research Effects of Parthenolide on Androgenetic Alopecia in Mice and Human Follicle Dermal Papilla Cells
Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.
research Inhibition of SARS-CoV-2 Entry Through the ACE2/TMPRSS2 Pathway: A Promising Approach for Uncovering Early COVID-19 Drug Therapies
Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.
research Premature Adrenarche, Polycystic Ovary Syndrome, and Intrauterine Growth Retardation: Does a Relationship Exist?
Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.
research Big Head? Bald Head! Skull Expansion: Alternative Model for the Primary Mechanism of Androgenetic Alopecia
The paper suggests that hair loss might be caused by skull growth, not just DHT's effect on hair follicles, and calls for more research.
research Polycystic Ovary Syndrome in Adolescence
PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.
research Physical Changes, Laboratory Parameters, and Bone Mineral Density During Testosterone Treatment in Adolescents with Gender Dysphoria
Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.
research Polycystic Ovary Syndrome in Adolescents
PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.
research Sex-Specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids
Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
research The Effect of Finasteride and Dutasteride on the Synthesis of Neurosteroids by Glioblastoma Cells
Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.
research The Probable Destructive Mechanisms Behind COVID-19 on Male Reproductive System and Fertility
COVID-19 may harm male fertility and damage the reproductive system.
research Sexual Desire in a Sample of Married Egyptian Women with Polycystic Ovarian Syndrome
Married Egyptian women with PCOS have lower sexual desire compared to those without PCOS.
research Pilosebaceous Unit: Structure, Function, and Disorders
Androgens and other hormones affect hair growth and skin conditions like acne.
research Prostaglandin-Induced Hair Growth
Latanoprost can make eyelashes longer, thicker, and darker.
research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
research T Helper 17 Cell/Regulatory T-Cell Imbalance in Hidradenitis Suppurativa/Acne Inversa: The Link to Hair Follicle Dissection, Obesity, Smoking, and Autoimmune Comorbidities
An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
research An Overview of Alopecias
The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.
research Drug-Induced Acne: Causes, Diagnosis, and Treatment
Some medications can cause acne, and stopping these drugs is the main treatment.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Phytochemical Studies on Traditional Herbal Medicines Based on Ethnopharmacological Information Obtained by Field Studies
Over 150 new molecules with biological activities were found in traditional herbal medicines, some with potential for new drug development.
research Hormonal and Reproductive Factors and Risk of Upper Gastrointestinal Cancers in Men: A Prospective Cohort Study Within the UK Biobank
Men with frontal male pattern baldness may have a higher risk of gastric cancer.
research Predisposing and Overall Effects of Reproductive Hormones on Breast Cancer: A Review
Reproductive hormones play a crucial role in breast cancer development and treatment challenges.
research Disappearance of a Virilizing Adrenal Tumor Following Therapy with Cyproterone Acetate
A woman's adrenal tumor disappeared after treatment with cyproterone acetate.
research The Connection of 5-Alpha Reductase Inhibitors to the Development of Depression
5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.
research Androgenetic Alopecia and COVID-19: Is There a Clinical Connection?
Androgenetic alopecia severity does not affect COVID-19 severity.
research Apoptosis in Hair and Skin: A Review
The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
research Understanding, Recognizing, and Managing Toxicities of Targeted Anticancer Therapies
Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
research Telomere Dynamics and Telomerase in the Biology of Hair Follicles and Their Stem Cells as a Model for Aging Research
Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
research Female Pattern Hair Loss: An Overview with Focus on the Genetics
Different genes cause Female Pattern Hair Loss compared to male hair loss, and treatments vary, but more research is needed to understand it fully.