Androgenetic Alopecia May Be Associated With Weaker COVID-19 T-Cell Immune Response: An Insight Into a Potential COVID-19 Vaccine Booster

November 2020 in “ Medical Hypotheses ”

Andy Goren, Flavio A. Cadegiani, Carlos Gustavo Wambier, Sergio Vano-Galvan, Antonella Tosti, Jerry Shapiro, Natasha Atanaskova Mesinkovska, Paulo Müller Ramos, Rodney Sinclair, Omar Lupi, Jana Hercogová, John D. McCoy

androgenetic alopecia T-cell immune response COVID-19 vaccine androgen receptor androgens AGA COVID-19

TLDR Hair loss may link to weaker COVID-19 immunity, suggesting possible need for extra vaccine boost.

There is a potential association between androgenetic alopecia (AGA) and a weaker T-cell immune response to COVID-19, which could impact the effectiveness of COVID-19 vaccines. The authors propose that a booster vaccine targeting the androgen receptor may be necessary for individuals with AGA to achieve adequate protection against the virus. Further studies are needed to determine the role of androgens and the androgen receptor in modulating the immune response to COVID-19.

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Research cited in this study

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research Androgenetic Alopecia Present in the Majority of Patients Hospitalized with COVID-19: The 'Gabrin Sign'

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 5 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community C’est terrible - at my wits end

in Female 443 upvotes 1 year ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

in Minoxidil 78 upvotes 1 year ago

A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

community Comprehensive Microneedling Guide

in Microneedling 293 upvotes 2 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

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in Treatment 42 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

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HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

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