Androgenetic Alopecia May Be Associated With Weaker COVID-19 T-Cell Immune Response: An Insight Into a Potential COVID-19 Vaccine Booster

    November 2020 in “ Medical Hypotheses ”
    Andy Goren, Flavio A. Cadegiani, Carlos Gustavo Wambier, Sergio Vano-Galvan, Antonella Tosti, Jerry Shapiro, Natasha Atanaskova Mesinkovska, Paulo Müller Ramos, Rodney Sinclair, Omar Lupi, Jana Hercogová, John D. McCoy
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    TLDR Hair loss may link to weaker COVID-19 immunity, suggesting possible need for extra vaccine boost.
    There is a potential association between androgenetic alopecia (AGA) and a weaker T-cell immune response to COVID-19, which could impact the effectiveness of COVID-19 vaccines. The authors propose that a booster vaccine targeting the androgen receptor may be necessary for individuals with AGA to achieve adequate protection against the virus. Further studies are needed to determine the role of androgens and the androgen receptor in modulating the immune response to COVID-19.
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