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ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.

Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Certain hormone treatments can improve acne and related conditions in women.

Topical finasteride helps regrow hair and reduce balding without side effects.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Chaga mushrooms contain compounds that may promote hair growth better than common treatments.

Testosterone helps human pancreatic cells increase insulin release.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Compounds from the Sansevieria trifasciata plant might be effective for treating hair loss.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Androgens can both increase and decrease hair growth in different parts of the body.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Finasteride safely lowers DHT levels without affecting testosterone.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.