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The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

FAI values above 6.4 may suggest high androgen levels and increased metabolic risks in Chinese women of reproductive age.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.

Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

Finasteride helps treat hair loss by blocking enzyme activity.

Both treatments reduced androgen levels and hair growth in women with hirsutism.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Finasteride side effects in young men may be linked to specific gene variations.

The T-zone on the face has more androgen receptors and produces more oil than the U-zone.

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

No clear link between androgen receptor variation and hair loss, but more research needed.

Androgen receptors found in monkey scalps, similar to humans, affect hair growth.

Androgen deprivation therapy might be better for preventing COVID-19 than treating it.