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The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.

Researchers created a new mouse model, G4, that mimics human PCOS symptoms and links the condition to a specific gene.

Insulin resistance and hyperinsulinism are linked to fertility issues and can worsen symptoms of PCOS.

High levels of androgens during early development may cause PCOS-like symptoms.

The T-zone on the face has more androgen receptors and produces more oil than the U-zone.

Dutasteride and finasteride affect different cell types differently.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Androgens may block hair growth signals, targeting this could treat hair loss.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Mutations in certain receptors can cause diseases and offer new treatment options.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

DHT stops hair regrowth in mice, similar to human hair loss.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.

Women with myotonic dystrophy might get diseases related to male hormones because their body tissues are extra sensitive to these hormones.