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Glioblastoma cells can make androgens, which might help the tumor grow.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Gene mutations can cause problems in male genital development.

DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

Some plants with flavonoids may help treat hair loss and promote hair growth.

Nourkrin® with Marilex® may increase hair count by 35.7% in postpartum hair loss.

Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.

Platelet factor 4 slows down hair growth and could make hair loss treatments more effective if removed.

A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.

Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

5α-reductase inhibitors like finasteride and dutasteride can help treat skin disorders stimulated by androgens, such as hair loss and acne.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.

Disrupting β-catenin signaling in certain cells causes anorectal malformations.

Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.

Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.