45 citations,
September 1998 in “Journal of Investigative Dermatology” The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
215 citations,
January 2011 in “Reproductive Biology and Endocrinology” About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.
62 citations,
April 2013 in “Steroids” PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.
27 citations,
January 1984 in “Pharmacology & Therapeutics” Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
January 2009 in “Egyptian Journal of Medical Human Genetics” The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.
174 citations,
November 2002 in “Expert Reviews in Molecular Medicine” Hair loss needs more research for better treatments.
441 citations,
May 2008 in “British Journal of Pharmacology” Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
16 citations,
September 2018 in “Journal of Ethnopharmacology” Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
43 citations,
April 2011 in “AJP Endocrinology and Metabolism” Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.
April 2020 in “International journal of reproduction, contraception, obstetrics and gynecology” A postmenopausal woman with hair loss and hirsutism improved after surgery to remove an ovarian tumor.
4 citations,
April 1999 in “Dermatologic Clinics” Androgens, like DHT, affect hair growth and treatments like finasteride may help.
131 citations,
September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
53 citations,
May 2010 in “PubMed” Spironolactone helps regrow hair in women with hair loss.
143 citations,
October 1996 in “Dermatologic Clinics” Too much androgen can cause hair loss; finasteride may help.
182 citations,
June 2002 in “Journal of Neuroscience” Androgens can help prevent memory problems caused by apoE4.
1 citations,
August 2023 in “Curēus” Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.
42 citations,
September 2007 in “The Journal of Clinical Endocrinology and Metabolism” The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.
67 citations,
July 2006 in “Clinics in Dermatology” Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.
January 2016 in “AACE Clinical Case Reports” Treatment restored normal sexual characteristics and blood condition in a patient with testicular cancer.
10 citations,
August 1991 in “PubMed” Inflammation, possibly triggered by a specific bacteria and activated by UV radiation, may contribute to male pattern baldness.
13 citations,
August 1991 in “The Journal of the American Osteopathic Association”
May 2023 in “International journal of pharmaceutical sciences and medicine” Sunflower oil was found to promote hair growth in mice with hormone-induced hair loss.
January 2020 in “International Journal of Applied Biology and P” Finasteride treatment for three years changes certain polyamine levels in the blood but not in urine.
22 citations,
September 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.
28 citations,
January 2003 in “Skin pharmacology and physiology” Melatonin affects skin cell growth differently based on how much and how long it's used.
21 citations,
January 2012 in “Annals of Dermatology” 17α-Estradiol solution safely improves hair density and thickness in female pattern hair loss.
9 citations,
June 2014 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Blood AMH levels are higher in women with PCOS than in those with other similar conditions.
34 citations,
March 2003 in “Veterinary Dermatology” Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.
6 citations,
August 2013 in “한국응용생명화학회지” Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.
November 2023 in “International Journal of Trichology” No significant link between hair loss and iron or thyroid levels was found, but checking for deficiencies might still be useful.