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Anti-androgen drugs can treat conditions like prostate cancer and male pattern baldness by blocking effects of testosterone and DHT.

Certain drugs that block specific enzymes can help treat prostate diseases.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Androgens can both increase body hair and cause scalp hair loss.

Hormonal therapies help treat female hair loss, but results are slow and vary.

Muscles can make their own androgens, which may help muscle growth.

A new method accurately measures nine specific hormones in human blood.

Dutasteride and finasteride affect different cell types differently.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.