research Repurposing Steroidogenesis Inhibitors for the Therapy of Neuropsychiatric Disorders: Promises and Caveats
Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
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research Novel Type 1 5a-Reductase Inhibitors With Antiproliferative Potential On LNCaP Cells
New compounds may help treat prostate cancer by reducing cell growth.
research A Study of the Androgen Receptor Gene Polymorphism and the Level of Expression of the Androgen Receptor in Androgenetic Alopecia Among Egyptians
The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.
research Redefining Hormone Resistance in Prostate Cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research Testicular Steroidogenesis: Production and Regulation of Testosterone and Dihydrotestosterone
Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
research Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin
Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
research Synthesis, Characterization and Evaluation of 5α, 6β-Dihalo Androsterone Derivatives as 5α-Reductase Inhibitors
Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.
research Antiandrogen And Hormonal Treatment Of Acne
Certain hormone treatments can improve acne and related conditions in women.
research Pharmacological Options for Treatment of Hyperandrogenic Disorders
Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
research 17α-Acetoxy-6-Bromo-16β-Methylpregna-4,6-Diene-3,20-Dione: A New Steroidal Derivative with High Antiandrogenic Activity
A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.
research Polycystic Ovary Syndrome: Comprehensive Overview and Diagnostic Criteria
PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.
research Use of Cyproterone Acetate in the Treatment of Acne, Hirsutism, and Virilism
Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
research Pre-Receptor Regulation of the Androgen Receptor
Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.
research Abiraterone and Spironolactone in Prostate Cancer: A Combination to Avoid
Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.
research A Role for Steroid 5 Alpha-Reductase 1 in Vascular Remodeling During Endometrial Decidualization
The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
research A Role for Steroid 5 Alpha-Reductase 1 in Vascular Remodeling During Endometrial Decidualization
The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
research Medical Management Options for Hair Loss
The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.
research Hormonal Therapy for Acne
Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.
research Dermatologic Manifestations of Polycystic Ovary Syndrome
Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.
research Female Hirsutism: Pathophysiological Considerations and Therapeutic Implications
Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
research Rooster Feathering, Androgenic Alopecia, And Hormone-Dependent Tumor Growth: What Is In Common?
Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.
research Management of Androgenetic Alopecia
Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.
research Androgen Treatment in Adolescent Males With Hypogonadism
Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Influence of Dosing Time on the Efficacy and Safety of Finasteride in Rats
Dosing time affects finasteride's effectiveness and safety in rats.
research Endocrine Evaluation of Hirsutism
Hirsutism, excessive hair growth in women, is often caused by PCOS and can be managed with medication and personalized treatment plans.
research Acne
Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
research Insulin Resistance and Polycystic Ovary Syndrome
Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.
research Androgenetic Alopecia in Men and Women
Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
research A Case Series of 20 Women with Hidradenitis Suppurativa Treated with Spironolactone
Spironolactone is an effective and well-tolerated first-line treatment for hidradenitis suppurativa in women.