January 2020 in “Archives of Medicine and Health Sciences” Certain immune molecules and stress affect hair loss, and while genes play a role, more research is needed to fully understand and treat it.
Targeting CXXC5 and GSK-3β may help treat male pattern baldness.
218 citations,
September 2012 in “Gastroenterology” Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
89 citations,
March 2001 in “Endocrine practice” The guidelines help doctors diagnose and treat hormone-related disorders in women.
50 citations,
May 2018 in “International journal of cardiology” Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.
35 citations,
January 2020 in “Skin Pharmacology and Physiology” The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
15 citations,
July 2017 in “Hormones” Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
15 citations,
April 2016 in “Hormones” Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.
10 citations,
January 2019 in “Archives of Endocrinology and Metabolism” Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.
9 citations,
February 2022 in “Biomolecules” Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.
5 citations,
July 2019 in “Nutrients” Low selenium intake may delay puberty in boys but not in girls.
2 citations,
May 2023 in “Current Nutrition Reports” Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.
2 citations,
January 2023 in “Pharmaceuticals” Natural products and phytochemicals may help with hair regrowth, but more research is needed.
2 citations,
January 2019 in “Egyptian Journal of Dermatology and Venereology” Insulin might be involved in causing hair loss and acne.
1 citations,
January 2024 in “International journal of molecular sciences” MicroRNAs could be key biomarkers and therapeutic targets for PCOS.
1 citations,
November 2023 in “Brain and behavior” Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.
1 citations,
April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
1 citations,
January 2023 in “Metabolites” Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.
1 citations,
August 2021 in “Arhivʺ vnutrennej mediciny” Hormonal imbalances can cause hair loss, and understanding them can help develop better treatments.
September 2024 in “Medicina” Certain gene variations may protect against skin issues and oxidative stress in women with PCOS.
August 2024 in “Drug Design Development and Therapy” Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
June 2024 in “Ecotoxicology and Environmental Safety” Finasteride harms Daphnia magna's reproduction, growth, and metabolism.
April 2024 in “Human genomics” Identified genes linked to male-pattern baldness may help develop new treatments.
December 2023 in “Regenerative therapy” miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
December 2023 in “Acta dermato-venereologica” Metformin might help treat certain skin conditions, but more research is needed.
Nanocarriers with plant extracts show promise for safe and effective hair growth treatment.
July 2023 in “Journal of Clinical Medicine” Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.
February 2023 in “Vaccines” COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.
July 2021 in “IntechOpen eBooks” Ginseng, especially its component ginsenosides, can promote hair growth, reduce hair loss, and potentially treat conditions like alopecia by affecting cell pathways and cytokines.