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Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Neurosteroids show promise for treating epilepsy and more research is needed.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Androgenic steroids can slow down or stop the growth of certain skin fungi.

Hair loss in men and women is linked to high stress hormone levels and other hormonal imbalances, suggesting treatments should be customized to each person's hormones.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.