Effects of Flutamide, a Pure Antiandrogen, on Endocrine Parameters in the Adult Female Rat
January 1987
in “
Gynecological Endocrinology
”
Flutamide antiandrogen endocrine parameters estrous cycle uterine estrogen receptors ovarian LH receptors ovarian FSH receptors plasma 17ß-estradiol levels ovarian progestins adrenal progestins androgens hirsutism contraception feminization fertility Flutamide antiandrogen hormone levels menstrual cycle estrogen receptors luteinizing hormone receptors follicle-stimulating hormone receptors estradiol levels progestins androgens excessive hair growth birth control feminization fertility
Studysummary This study found that treatment with the pure antiandrogen Flutamide did not affect the estrous cycle or plasma levels of most hormones in female rats, supporting its potential use for treating hirsutism, acne, and alopecia in women.
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