4 citations
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January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that the FSHR Ser680Asn (rs6166) gene polymorphism is associated with an increased risk of PCOS in the examined population and could serve as a molecular biomarker for identifying risk.
February 2016 in “Evidence Based Women Health Journal (Online)” This study observed that women with polycystic ovarian syndrome had higher serum SRAGE levels compared to controls, but the difference was not statistically significant.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” In this study, using a 3D culture model, researchers observed that developmental stage and androgen levels influenced murine follicle growth, which may inform treatment for women with low ovarian reserve but cautions against excessive androgen exposure.
2 citations
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August 2021 in “Experimental and Therapeutic Medicine” This study suggested that moxibustion treatment before or at the early stage of diminished ovarian reserve in rats may improve ovarian function by modulating androgen balance, though its effects differ across intervention timings.
8 citations
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January 1987 in “Gynecological Endocrinology” This study found that treatment with the pure antiandrogen Flutamide did not affect the estrous cycle or plasma levels of most hormones in female rats, supporting its potential use for treating hirsutism, acne, and alopecia in women.