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Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Tofacitinib may effectively treat hair loss and improve symptoms in autoimmune conditions like alopecia areata and Sjögren's syndrome, but long-term treatment might be necessary.

Digital gangrene can be a rare first sign of late-onset systemic lupus erythematosus.

SLE should be considered in unexplained fevers, even in males.

Sertraline, an antidepressant, may cause hair loss in rare cases.

TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.

Ethosomes can safely and effectively deliver various drugs deep into the skin.

Different small areas within hair follicles send specific signals that control what type of cells stem cells become.

Bariatric surgery can cause serious mineral deficiencies, requiring better patient education and monitoring.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

The guidelines help doctors diagnose and treat hormone-related disorders in women.

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

DPCP is effective for treating severe alopecia areata, but relapse is common.

BMP signaling is essential for the development of touch domes.

Fat under the skin releases HGF which helps hair grow and gain color.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

Dermal papilla cell vesicles can boost hair growth genes in fat stem cells.

Patients with RASopathies are at risk for autoimmune disorders and should be routinely screened.

The true incidence of post-Finasteride syndrome is unclear, and more research is needed.

MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.

The document concludes that diagnosing and treating Interstitial Pneumonia with Autoimmune Features (IPAF) is challenging, needs a multidisciplinary approach, and further research for better diagnostic criteria and treatments. It also emphasizes regular checks for Connective Tissue Disease symptoms in all patients with Interstitial Lung Disease.

Platelet-rich plasma may improve wound healing by stimulating cell growth and blood vessel formation.

Wharton's jelly-derived stem cells were safely used to treat four alopecia patients, resulting in hair regrowth in all of them.

Cyclosporine-A can cause serious blood clots in the brain, so patients need careful monitoring.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Certain genetic markers can indicate higher or lower risk for systemic lupus erythematosus.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Certain miRNAs play a key role in the growth of cashmere by affecting hair follicle development and regeneration.