A Rare Case of Cutis Verticis Gyrata with Underlying Cerebriform Intradermal Nevus

    December 2019 in “ Cureus
    Lisa Fronek, Katherine Braunlich, Maheera Farsi, Richard A. Miller
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    TLDR A patient with a scalp condition and benign skin tumor experienced hair loss and did not improve with treatment, choosing not to have surgery despite a small cancer risk.
    In 2019, researchers reported a rare case of a 46-year-old female patient with Cutis Verticis Gyrata (CVG), a scalp disorder characterized by brain-like folds in the skin. This patient's CVG was secondary to an underlying cerebriform intradermal nevus (CIN), a benign skin tumor. The patient experienced generalized hair loss over nine months, diagnosed as telogen effluvium, a common form of hair loss. Despite treatment with clobetasol 0.05% scalp solution, biotin 5,000 µg daily, and tricomin shampoo, there was no significant improvement. The patient was informed about surgical treatment options and the 4.5% risk of malignant melanoma developing within the CIN, but chose not to pursue further evaluation and treatment. The study emphasized the need for further discussion on the best approach for such cases, considering the low rate of malignant change and the extensive surgical margins involved with CVG.
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