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The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

DHT inhibition may increase spinal bone growth in ankylosing spondylitis.

High levels of anti-Müllerian hormone can indicate polycystic ovarian syndrome in women who can have babies.

Agaricus subrufescens improves ovarian function and biochemical health in rats with PCOS.

Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.

PCOS patients have more central body fat, which can be effectively measured using DEXA.

Oxytocin may help hair grow by increasing hair growth-related genes and factors.

Mutations in mitochondrial DNA might significantly contribute to the development of Polycystic Ovarian Syndrome.

Polycystic ovary syndrome is a common hormonal disorder in women that affects health and fertility.

Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.

People with early-onset androgenetic alopecia may have a higher risk of heart disease due to abnormal blood lipid levels.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Testosterone's effects on COVID-19 are unclear and need more research.

The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Gut microbes significantly affect brain steroid levels.

The article suggests renaming Polycystic Ovarian Syndrome (PCOS) to "Hyperandrogenic Persistent Ovulatory Dysfunction Syndrome" (HA-PODS) for accuracy and consistency, but no final decision was made.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

Quercetin may help improve symptoms of polycystic ovary syndrome.

Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.

Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.

Polycystic ovary syndrome and iron overload share similar symptoms and can be potentially treated with blood removal, diet changes, and probiotics.

Polycystic Ovary Syndrome (PCOS) was found in 3.86% of tenth-grade girls in Guangzhou, China, with higher rates in overweight and obese girls, suggesting diagnosis should focus on hyperandrogenemia.

Overweight PCOS patients often have skin issues like acne, but all PCOS patients should get lifestyle advice.

The study found that PCOS affects about 6.5-6.8% of women in both urban and rural areas of Telangana, India, and highlighted the importance of lifestyle changes for management.