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Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Hedgehog signaling in certain cells is crucial for hair growth during wound healing.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.

CD90 is present on specific cells in dog hair follicles.

Placental mesenchymal stem cells and their conditioned medium significantly improve healing in local radiation injuries.

The document describes various skin conditions, their features, and treatments but lacks detailed study size information.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Targeting NETs may help reduce fibrosis in Crohn's disease.

Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Targeting the skin's endocannabinoid system could help treat skin disorders.