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    Glossary Adaptive Immunity

    system learns to recognize and remember specific pathogens

    Adaptive immunity, also known as acquired immunity or specific immunity, is the part of the immune system that learns to recognize and remember specific pathogens. Unlike innate immunity, which provides a general defense, adaptive immunity tailors its response to each unique invader, improving its effectiveness over time. This system involves specialized cells like T cells and B cells, which can remember past infections and provide a faster, more robust response upon subsequent exposures.

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    1. Genome-wide association study in alopecia areata implicates both innate and adaptive immunity Nature · 2010 · 717 citations
    2. Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    3. Understanding autoimmunity of vitiligo and alopecia areata 2016 · 74 citations
    4. Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing Science Advances · 2021 · 66 citations
    5. Resident Memory T Cells in Autoimmune Skin Diseases Frontiers in immunology · 2021 · 50 citations
    6. Alopecia Areata: An Autoimmune Disease of Multiple Players ImmunoTargets and therapy · 2021 · 31 citations
    7. The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier Frontiers in Immunology · 2021 · 23 citations
    8. Peripheral blood gene expression in alopecia areata reveals molecular pathways distinguishing heritability, disease and severity Genes and Immunity · 2010 · 20 citations
    9. Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 2 citations
    10. Psoriasis and Related Disorders 2024 · 1 citations
    11. Autoimmune skin disease pathogenesis: a chronological immune cascade and multi-hit model Immunity & Inflammation · 2026
    12. CAQ Corner: Basic concepts of transplant immunology Liver transplantation · 2022
    13. Abstract 1219: Defective catagen entry in EGFR deficient skin precedes cutaneous inflammation Cancer Research · 2012
    14. 489 Seborrhea-like dermatitis phenotype in the Mpzl3 knockout mice 2016
    15. Data from: Systemic humoral activation facilitates tissue regeneration by D-chiral biomaterial scaffolds Research Data Repository, Duke University · 2026
    16. Unraveling the web of defense: the crucial role of polysaccharides in immunity Frontiers in Immunology · 2024 · 49 citations
    17. The X Factor in Immunity: Sex Differences Shaped by the X Chromosome Immunological Reviews · 2026
    18. Evidence on Hidradenitis Suppurativa as an Autoinflammatory Skin Disease Journal of Clinical Medicine · 2024 · 9 citations
    19. Vitamin D in trichology: a comprehensive review of the role of vitamin D and its receptor in hair and scalp disorders Giornale italiano di dermatologia e venereologia · 2020 · 2 citations
    20. “Structural imprinting” of the cutaneous immune effector function Tissue Barriers · 2020 · 4 citations
    21. The role of B cell-activating factor system in autoimmune diseases: mechanisms, disease implications, and therapeutic advances Frontiers in Immunology · 2025 · 4 citations
    22. An outline of SARS-CoV-2 pathogenesis and the complement cascade of immune system 2021 · 6 citations
    23. No evidence for the immunocompetence handicap hypothesis in male humans Scientific Reports · 2018 · 87 citations
    24. Group IID, IIE, IIF and III secreted phospholipase A2s Biochimica and biophysica acta. Molecular and cell biology of lipids · 2018 · 23 citations
    25. Under Development JAK Inhibitors for Dermatologic Diseases Mediterranean Journal of Rheumatology · 2020 · 14 citations
    26. Resident macrophages of the lung and liver: The guardians of our tissues Frontiers in Immunology · 2022 · 4 citations
    27. Nitric Oxide Signal Transduction and Its Role in Skin Sensitization Biomolecules & therapeutics · 2023 · 1 citations
    28. Disturbance of Immune Microenvironment in Androgenetic Alopecia through Spatial Transcriptomics International Journal of Molecular Sciences · 2024
    29. Sex Hormones and their Analogues in Neuroimmune Biology Immunology Endocrine & Metabolic Agents - Medicinal Chemistry · 2010 · 9 citations
    30. Extraskeletal actions of vitamin D Annals of the New York Academy of Sciences · 2016 · 119 citations