June 2020 in “Aesthetic Surgery Journal” This study found that PRP with high estrogen levels increased hair density more effectively and earlier than autologous PRP in male patients with androgenic alopecia.
136 citations
,
April 2016 in “Dermatologic Surgery” This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.
119 citations
,
January 2014 in “Indian Journal of Dermatology, Venereology and Leprology” This review discusses the use of platelet-rich plasma in various dermatological applications and reports no new clinical results; the authors call for more rigorous trials to confirm its effectiveness.
115 citations
,
August 2020 in “International Journal of Molecular Sciences” This systematic review indicates that a platelet-rich plasma concentration of 1.0 × 10^6 plt/μL may be optimal for tissue regeneration due to sufficient nutrition supply and effective growth factor diffusion in vivo.
65 citations
,
April 2020 in “International Journal of Molecular Sciences” This review indicates that most studies reported positive effects of platelet-rich plasma injections for treating androgenic alopecia, with no major side effects, suggesting it may be a safe alternative to Minoxidil and Finasteride.
57 citations
,
May 2016 in “Journal of Dermatological Treatment” This analysis suggests that platelet-rich plasma therapy may be promising for treating androgenetic alopecia, but further controlled trials with standardized measures are needed to confirm its efficacy.
29 citations
,
September 2020 in “International Journal of Molecular Sciences” This review outlines the current state of freeze-dried platelet-rich plasma (FD-PRP) research, emphasizing its use in wound healing, lumbar fusion, knee conditions, and dentistry, but reports no new clinical findings.
21 citations
,
June 2019 in “Dermatologic Surgery” This research review found that platelet-rich plasma treatment generally produced successful hair regrowth in both androgenetic alopecia and alopecia areata, despite study differences that limited direct statistical comparison.
19 citations
,
August 2019 in “Seminars in Plastic Surgery” This review explains the biology and preparation of platelet-rich plasma and discusses its clinical applications in plastic surgery, but reports no new findings.
12 citations
,
December 2017 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses platelet-rich plasma and microneedling for alopecia areata, reporting promising small-scale findings but no new results, and suggests further trials to determine efficacy and specific disease subtype suitability.
9 citations
,
September 2019 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma injections significantly increased hair density in men with androgenetic alopecia compared to placebo, but further research is needed to understand factors influencing treatment success.
8 citations
,
August 2020 in “Experimental dermatology” This study observed that platelet-rich plasma samples from female patients show significant variability in growth factor secretion, which may influence the inconsistent clinical response in alopecia treatment.
6 citations
,
March 2021 in “Journal of Cosmetic Dermatology” In this study, platelet-rich plasma treatment improved hair regrowth and characteristics in mice and showed therapeutic efficacy in Chinese patients with androgenetic alopecia.
4 citations
,
December 2019 in “Skin appendage disorders” In this study, manually prepared platelet-rich plasma did not show significant improvement in hair count or anagen hair proportion for men with androgenetic alopecia.
4 citations
,
January 2015 in “Journal of clinical & experimental dermatology research” This study observed a slight improvement in hair density in men with androgenetic alopecia treated with autologous platelet rich plasma, but only two cases showed cosmetic improvement.
3 citations
,
December 2018 in “International Journal of Biomedicine” This study found that treating androgenetic alopecia with platelet rich plasma increased hair density and diameter while decreasing the proportion of telogen and vellus hairs.
2 citations
,
November 2023 in “Curēus” This review explores platelet-rich plasma's role in wound healing and discusses its potential as a broadly applicable therapeutic option, but it reports no new clinical results.
1 citations
,
February 2020 in “International journal of research in dermatology” This review discusses the potential applications of platelet rich plasma in dermatology and cosmetology for conditions like alopecia and skin rejuvenation and reports no new clinical findings.
1 citations
,
November 2017 in “Journal of Investigative Dermatology” This review discusses the potential use of platelet-rich plasma and microneedling for alopecia areata and reports encouraging findings, but no new clinical results; future research is needed to validate these treatments.
January 2025 in “Journal of Plastic Reconstructive & Aesthetic Surgery” Two L-PRP treatments improve hair density in mild to moderate alopecia.
January 2019 in “Georg Thieme Verlag eBooks” This review suggests that platelet-rich plasma therapy shows promise for androgenetic alopecia and may be effective for some alopecia areata and cicatricial alopecia cases, but more robust trials are needed.
July 2018 in “Elsevier eBooks” This review discusses novel treatments for androgenetic alopecia, including therapies like platelet-rich plasma and adipose-derived stem cells, and reports no new clinical results.
May 2015 in “Hair transplant forum international” This article contains no research findings; it reports on an online discussion about platelet-rich plasma (PRP) and opinions shared during a conference.
March 2021 in “British Journal of Dermatology” This study using a humanized mouse model of androgenetic alopecia suggests that platelet-rich plasma may promote hair regrowth and improve hair characteristics in vivo.
October 2020 in “Journal of Pakistan Association of Dermatology” This study found that platelet-rich plasma therapy was more effective in increasing hair count than topical 5% minoxidil lotion in men with androgenetic alopecia.
53 citations
,
June 2017 in “Skin appendage disorders” This review suggests that platelet-rich plasma may be effective in increasing hair density in patients with androgenetic alopecia, but more research is needed to determine the best treatment protocol.
2 citations
,
June 2024 in “Regenerative Therapy” In this study, ozone treatment was shown to increase the concentration of growth factors like EGF and TGF-β in PRP in vitro, suggesting that oxygen-rich PRP injections may provide an effective method for facial rejuvenation.
14 citations
,
October 2020 in “Natural Products and Bioprospecting” This review discusses current topical treatments, natural products, and complementary therapies for androgenetic alopecia, but it reports no new clinical results.
6 citations
,
April 2022 in “Cellular and Molecular Life Sciences” This study reports that a new protocol using Angio PRP improved wound healing in mice by enhancing key healing processes and regulating inflammation, suggesting potential for clinical advancements.
3 citations
,
December 2016 in “Blood” This study found PRP treatment significantly increased hair count and anagen hairs in male patients with androgenetic alopecia, but there was no correlation between therapeutic response and platelet or growth factor levels.