Treatment of Male-Pattern Alopecia with Platelet-Rich Plasma

December 2019 in “ Skin appendage disorders ”

Aline Lissa Okita, Denise Steiner, Sineida Berbert Ferreira, Paulo Müller Ramos, Walter Motta Ferreira, Rebecca Impelizieri Silveira, Maria Carolina Martins Mussi, Ricardo Vaidergorn, Rachel Ferreira

androgenetic alopecia platelet-rich plasma anagen hairs AGA PRP

Studysummary In this study, manually prepared platelet-rich plasma did not show significant improvement in hair count or anagen hair proportion for men with androgenetic alopecia.

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The 2020 study "Treatment of Male-Pattern Alopecia with Platelet-Rich Plasma" involved 20 male patients with Androgenetic Alopecia (AGA) who were treated with 3 monthly injections of Platelet-Rich Plasma (PRP). However, the study found no statistically significant improvement in hair count or proportion of anagen hairs. The researchers suggested that the lack of significant results could be due to variables in PRP preparation or the small number of patients. They recommended further studies to establish a standardized and effective PRP protocol.

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research Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature and Proposed Treatment Protocol

45 citations , September 2018 in “International Journal of Women's Dermatology”

This review discusses the use of platelet-rich plasma as a treatment for androgenetic alopecia and highlights the need for standardized protocols, reporting no new clinical results.

research Systematic Review of Platelet-Rich Plasma (PRP) Preparation and Composition for the Treatment of Androgenetic Alopecia

37 citations , May 2018 in “Journal of Cosmetic Dermatology”

This review analyzed clinical trial protocols for platelet-rich plasma preparation in hair loss treatment, finding inconsistent and insufficient reporting that complicates comparison and efficacy determination.

research Effectiveness of Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature

53 citations , June 2017 in “Skin appendage disorders”

This review suggests that platelet-rich plasma may be effective in increasing hair density in patients with androgenetic alopecia, but more research is needed to determine the best treatment protocol.

research The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis

178 citations , April 2017 in “Journal of The American Academy of Dermatology”

This systematic review and meta-analysis found that minoxidil, finasteride, and low-level laser light therapy significantly improve hair growth in men with androgenetic alopecia, while minoxidil is also effective for women, compared to placebo.

research Platelet-Rich Plasma for Androgenetic Alopecia: Does It Work? Evidence from Meta-Analysis

64 citations , March 2017 in “Journal of Cosmetic Dermatology”

This meta-analysis suggests that local injection of platelet-rich plasma for androgenic alopecia is associated with an increased number of hairs and some increase in hair thickness, though larger studies are needed for confirmation.

Evaluation of Non-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems

research Evaluation of Non-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems

136 citations , February 2017 in “International Journal of Molecular Sciences”

This study observed that autologous platelet-rich plasma treatment improved hair count and density in areas with androgenetic alopecia compared to placebo, with differing outcomes based on the PRP collection device used.

research Platelet-Rich Plasma by Single Spin Process in Male Pattern Androgenetic Alopecia: Is It an Effective Treatment?

27 citations , January 2017 in “Indian Dermatology Online Journal”

This study found no significant benefit from PRP injections for treating androgenetic alopecia in men, highlighting the need for larger, well-designed trials to assess its effectiveness and safety.

research Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia

87 citations , September 2016 in “Dermatologic Surgery”

This study found that platelet-rich plasma did not significantly improve hair mass index or hair count in women with female androgenetic alopecia, though some patients perceived benefits in hair quality.

research Efficacy of Platelet-Rich Plasma in the Treatment of Androgenetic (Male-Patterned) Alopecia: A Pilot Randomized Controlled Trial

61 citations , September 2016 in “Journal of Cosmetic and Laser Therapy”

This study found that platelet-rich plasma was not effective in treating androgenetic alopecia in men with grade 4–6 hair loss.

research The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

183 citations , January 2014 in “BioMed Research International”

This study reported that AA-PRP injections significantly increased hair count and density in individuals with pattern hair loss compared to baseline, demonstrating their potential for enhancing hair growth.

Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period

research Growth Factor and Growth Factor Receptor Localization in the Hair Follicle Bulge and Associated Tissue in Human Fetus

94 citations , March 1996 in “Journal of Investigative Dermatology”